Therapeutic risk score for pharmaceutical follow-up prioritization.

Abstract

Objective: To develop an instrument for evaluating pharmacotherapeutic risk factors (score) to prioritize patients in pharmacotherapeutic monitoring. Methodology: An analysis of the Martinbiancho¹ methodology was developed, considered as a model study focusing on the need for parameter modifications according to the profile of pediatric patients treated at the Hospital Geral do Grajaú. Associated with data from the methodology used as a model, a literature review was  made regarding risk factors for the pediatric population in relation to the use of medications, pharmacokinetics, pharmacodynamics, polypharmacy, risk of adverse reactions to medications and regarding clinical pharmacy . The following factors were found: age, polypharmacy, use of high-alert medications, use of intravenous medications, route of feeding (tubes and parenteral nutrition), liver and kidney failure, heart and lung problems. It was decided to add the use of screening medications, use of antibiotics, use of sedoanalgesic and/or vasoactive medications and non-standardized medications in the institution. In total, 11 important parameters in pediatrics were selected.Results: After choosing the criteria considered relevant, a form was developed to apply the score.Conclusion: The obtained score is expected to be an efficient instrument for detecting and prioritizing patients at greater risk of developing drug-related problems (DRPs), enabling a greater contribution to care in relation to therapeutics for the pediatric population.